Beilstein J. Org. Chem.2021,17, 410–419, doi:10.3762/bjoc.17.37
ring at the C6 position of purine to act as leaving group.
Keywords: 2,6-bistriazolylpurines; nucleophilic aromatic substitution; purine nucleosides; triazoles; Introduction
Modified purine derivatives are an important class of compounds which possess a wide spectrum of biological activities [1][2
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Graphical Abstract
Scheme 1:
Synthetic pathways for the synthesis of 6-substituted 2-triazolylpurine derivatives IV.